Wednesday, May 19, 2010

Pharma Stocks to Watch Ahead of Key FDA Meetings

The road to FDA approval isn't Gardening artalways an easy one and is often fraught with road blocks like advisory committee meetings. These meetings are held when the FDA has a few questions about a New Drug ApplicationWorld~~~Crime that a company has submitted, giving a panel of experts in the given field a chance to grill the company about the drug candidate. The FDA doesn't have to follow the decision of these committees, but don't be fooled, the agency often doesn't stray from the panel's choice.ModernMusclecars Not only do these meetings have a major effect on whether or not a drug will eventually be approved, but they also have the ability to tank a stock or make it soar in a matter of hours. Keeping tabs on when the advisory committees will be reviewing the stocks in Unbelieveble Muslims your portfolio is key to knowing when to up your ante or when to cut your losses.QuestCor is now seeking the approval of the drug for infantile spasms, a seizure House building disorder seen in children. The drug is already widely prescribed for the off-label use in the treatment of infantile spasms, but QuestCor currently doesn't have the right to promote the drug for that indication. The FDA already denied approval of Acthar for the treatment of IS in May 2007. Expect a more positive outcome this time around, but don't expect the company to make that much more money off of this indication. Final word on approval of the drug will likely be given by the FDA by June 11.
May 12: The joint meeting of the Arthritis Advisory Committee and the Drug Safety and Risk Management Committee will meet at 8 a.m. EST on this date to access the viability of NicOx's (COX) osteoarthritis drug naproxcinod. The company expects to hear a final decision from the FDA by July 24.A few short weeks after the company announced that the FDA required an advisory committee meeting, NicOx released the results of a phase III study showing that naproxcinod performed better than a placebo. The study also showed that naproxcinod didn't adversely affect the blood pressure of patients like naproxen has been known to do. Naproxen is a widely prescribed nonsteroidal anti-inflammatory.
Nothing contained in this article is intended as a solicitation for business of any kind or for investment in the firm.
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Pakistan: 41 militants, 2 soldiers die in fighting

PARACHINAR, Pakistan – More than House building 100 militants armed with rockets and automatic weapons attacked two security checkpoints in northwestern Pakistan on Monday, sparking intense fighting that left at least 41Martialarts insurgents and two soldiers dead, officials said.
The clashes were the latest violence in the Orakzai tribal region, where the military launched an operation in March to rout Pakistani Taliban fighters who have fled there to escape other offensives. More than 300 suspectedsurfing ocean militants have been killed in three weeks of constant airstrikes and occasional ground clashes.The U.S. has applauded Pakistan's push to go after militants in the volatile border area near Afghanistan. But American officials would like the country to do more to target those fightersChasing the Sun who have been staging cross-border attacks against U.S. and NATO troops in Afghanistan.Security forces successfully repelled the attacks early Monday morning against checkpoints in the villages of Shireen Dara and Sangrana in Lower Orakzai, local administrator Touching your nerve Samiullah Khan said. Three soldiers were wounded in the fighting, he said.
"More then 100 militants attacked the security checkpoint in Shireen Dara," Khan said. "They fought a gunbattle for two hours and fired several rockets."After the battles subsided, authorities found the bodies of 15 dead militants around the two checkpoints, said two intelligence officials. Insurgents removed the bodies of at least 26 others who were killed, they said, speaking on condition of anonymity because they were not authorized to talk to the Fighter jets destroyed three militant hie-outs in Sangram village in Orakzai on Sunday, killing 10 suspected insurgents, Khan said. A day earlier, similar strikes killed nearly 100 suspected militants in the Orakzai and Khyber tribal areas, according to officials.
Government reports are almost impossible to independently verify because journalists are prohibited from traveling to the country's semiautonomous tribal areas.
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Clinton says US joins Poland in mourning

WASHINGTON (AP) — U.S. Secretary of Statehigh in the sky Hillary Rodham Clinton says the Polish leaders who were killed in a plane crash Saturday leave behind "a legacy that will live forever."Clinton visited the Polish embassy in Washington on Sunday to sign a condolence book commemorating the deaths of Poland's presidentPopular Chinese, Lech Kaczynski, and dozens of other Polish political, military and religious leaders in the plane crash in Russia.
The secretary told Robert Kupiecki, Poland's ambassador to the United States, that Polish Americans as well as "every American who admires what Poland has built" are joining his nation in mourning.Clinton promised that the U.S. wouldNatural disaster work with Poland "to build that future that the people on that plane gave their lives forAfghan official: 4 civilians killed by NATO troopsKABUL – Interntional troops home decorations opened fire on a civilian bus early Monday in a southern Afghan city, killing four people and wounding 18, the local governor's spokesman said. Gardening art
NATO was sending investigators to the scene but didn't immediaThe governor's spokesman, Zelmai Ayubi, said the shooting occurred soon after daybreak and that international troops took 12 of the wounded to a military hospital.
Ayubi said the provincial government strongly condemned the shooting.
NATO spokesman Mst. Sgt. Jeff Loftin said the alliance had dispatched a team to the scene to investigate. He said the local command in Kandahar had no further information on what happened.The top NATO commander in Afghanistan, U.S. Gen. Stanley McChrystal, has issued strict orders to his troops to try to reduce civilian casualties. But these still occur regularly, unleashing raw emotions that highlight a growing impatience with coalition forces' inability to secure the nation after more than eight years of war.
The support of the local population in Kandahar is seen as essential for the success of a long-anticipated allied operation to clear the biggest city in the south of Taliban insurgents.
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GOP senators push for `mainstream' court nominee

WASHINGTON – GOP senators whodiscuss my future will help shape the review of President Barack Obama's next nominee to the Supreme Court said Sunday he must pick someone with "mainstream" judicial views to avoid a potential filibuster.
Sen. Jeff Sessions of Alabama, the top Republican on the Senate Judiciary Committee, wouldn't rule out using that tactic to "protect the Constitution" from a high court nominee who, he said, would make law rather than interpret it. fly to paris
Whether there's a drawn-out fight over a successor to retiring Justice John Paul Stevens, the leader of the court's liberal wing, "is in the president's hands," Sessions said. Stevens plans to step down when the court finishes its work for the summer.life is a joke
Added Arizona Sen. Jon Kyl, the Senate's second-ranking Republican and a committee member: "I'm not going to take it off the table. But I think it can easily be avoided."That led a committee Democrat, Sen. Charles Schumer of New York, to claim that A Midsummer Night's Dream"it's just about a certainty that the president will nominate someone in the mainstream, so the likelihood of a filibuster is tiny." give me your song

Kyl said it would take "extraordinary circumstances" to compel a GOP filibuster. Republicans are likely to echo those terms — judicial mainstream and extraordinary circumstances — during the confirmation process. Just as likely is disagreement between Republicans and Democrats over how the nominee's views fit those terms.Sen. Patrick Leahy, the chairman of the Judiciary Committee, predicted that Obama will nominate Stevens' replacement in time for hearings to wrap up this summer and for the nine-member court to be at full strength for the fall term.
"He wants somebody who has a sense of what real life is in America," said Leahy, D-Vt. Calling a filibuster "the lazy person's way out," the senator said he didn't think there would be one.In 2005, when Democrats were in the minority in the Senate and some of President George W. Bush's picks for the federal bench were stalled, a group of 14 centrist Republicans and Democrats agreed not to prevent a vote on judicial nominees except under extraordinary circumstances. Exactly what constituted such circumstances was not part of the compromise.
Now in the minority, Republicans fiercely opposed Obama's first Supreme Court nominee, Sonia Sotomayor, last year. The Senate voted 68-31 — all but nine Republicans were against her confirmation — in her favor.With the election in January of Sen. Scott Brown, R-Mass., erasing the Democrats' filibuster-proof majority, Republicans could unite to block a vote on the next confirmation if all 41 Republicans were to agree.
"If we have a nominee that evidences a philosophy of judges know best, that they can amend the Constitution by saying it has evolved, and effectuate agendas, then we're going to have a big fight about that because the American people don't want that," Sessions said.
Sessions and Leahy appeared on NBC's "Meet the Press" while Kyl and Schumer were on ABC's "This Week."http://forums.premiere.com
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Thursday, May 6, 2010

Sex slave girls face cruel justice in Iraq

At one of Baghdad's two female juvenile prisons, the young Iraqi girls live in limbo, sadness and desperation permeating every aspect of their interrupted lives.
Some face punishment for prostitution. Others are charged with ties to terrorism. And then there are the victims, also behind bars.
Fifteen-year-old Zeina's sad journey to prison began two years ago when she says was sold into sex slavery. "My father came and took me to go visit my grandfather in Syria," says Zeina, "and I went with him."
The family trip turned out to be a cover story, and Zeina found herself faced with the most horrific possible reality. She says she was then forcefully taken from Syria to the United Arab Emirates and sold into sexual slavery.
But Zeina refused to surrender to such a horrendous fate. And when the opportunity presented itself, she ran away. "I'm proud of myself," explains Zeina. "I turned myself into the police and decided not to stay in that situation."
Authorities in Dubai helped her return to Iraq, but more cruelty awaited her in Baghdad. The only way Zeina could make it home was to travel on a forged passport -- a very serious crime in Iraq.
After escaping her ordeal, Zeina found herself being prosecuted, rather than being comforted. As punishment, she's now serving two years in jail. A prison official confirmed her story.
Iraqi women's rights activists are outraged. "She refused to accept that her body had been sold. So this is how they reward her?" said Dalal Rubaie with the Organization for Women's Freedom in Iraq, "To put her in jail for two years? Where's the justice?"
Trafficking is a growing problem in Iraq. Some vulnerable women, desperate to support their families, are tricked into it by accepting fake marriage proposals. Many young girls, their parents facing dire economic circumstances, are just sold outright.
"In some ways, their fate is worse than death," explained Samer Muscati from Human Rights Watch. "Once they've been trafficked, there's a stigma even though they're the victims in this horrific situation. They've been exploited and they've been trafficked to another country with no real recourse."
According to Muscati, even if the girls do manage to escape the cruelty of their circumstances, it will be very difficult for them to escape the judgment of their families.
"When they do come back to Iraq, if the family does accept them it's very difficult because they've brought great shame to the family, they're subjected to honor crimes. And we've come across cases where young women have preferred to stay in prison or custody than to be released and to face tribal justice," Muscati said.
Rubaie puts it even more bluntly when discussing what little future awaits trafficked girls who manage to return home.
"I'm sure the girl's family won't take care of her," said Rubaie. "I'm sure that neighbors and relatives and society will judge her, they'll know that the girl had been a prisoner and the family will be ashamed of her.
"I'm sure they won't let her travel. I'm sure she won't be able to complete her education, if she had been studying. Or they will force her to marry a cousin so they can exert control over her. Any cousin. They'll end her life."
A sense of injustice pervaded every story told by the prisoners. Some inmates had actually discovered they were to be trafficked and tried to stop it.
When Fatin found out her father was attempting to sell her, she immediately sought help from the law.
"I ran away from Najaf and escaped to Baghdad where I found my mother and asked her if she knew what my father was planning," says 22-year-old inmate Fatin, "So she took me to court in Baghdad, we got a lawyer and brought a case against my father."
Months passed and the lawsuit was never heard. While awaiting justice, Fatin says her father raped her. After the attack, she killed him, was tried, and is currently serving the fifth year of a 15 year sentence.
Muscati, who's studied trafficking extensively in Iraq, can't understand why Iraqi officials aren't doing more to stop it.
"Why is the Iraqi government not prosecuting the traffickers?" Muscati asked. "There hasn't been a case of prosecution against a trafficker that we're aware of. Why is the Iraqi government not passing a law to make it more difficult for trafficking?"At 22, Fatin, like several of her fellow inmates, is too old to remain in a juvenile facility. She'll soon have to serve out the rest of her term in a prison for adults, a much harsher environment.
Qassim Abdul Ameer, warden of the juvenile prison, is worried for Fatin and other inmates in the same situation. "Of course she will find it difficult there," Abdul Ameer says about Fatin, "because the environment will be difficult there. In the adult prisons, they usually take advantage of the younger girls."
Fatin does fear the transfer, but it's her eventual release still a decade away that she's even more afraid of.
"Yes, there is freedom outside," says Fatin, "but people don't forgive. They don't have mercy."
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Hawking: Time travel will happen

There's something very comforting when a scientist as well regarded as Stephen Hawking admits to keeping quiet for fear of "being labeled a crank."
Thankfully, he seems to have conquered his fears in a new documentary series for the Discovery Channel, in which he has already considered how man might truly conquer space. Or, indeed, how spacemen might come down to our meager Earth and dismember us as so much fast food.
Hawking has already warned in his documentary that we should be very wary about making contact with beings from out there. "If aliens ever visit us, I think the outcome would be much as when Christopher Columbus first landed in America, which didn't turn out very well for the Native Americans," he said in "Stephen Hawking's Universe."
But, as he presented his latest ideas about what travel in the future might resemble, he reportedly admitted that he had kept quiet on the subject for fear of being labeled a heretic by the scientific community.
One day, we will boldly go. Well, you might.(Credit: CC Guy David/Flickr)
Thrusting off his heretical shackles, he reportedly suggested that spaceships will one day be so fast that we won't know whether we've come or gone. Hawking suggests that Einstein's theories of relativity will become as relatively obsolete as, who knows, the home phone. He posits that, at some point when we're all long gone, a day on a spaceship traveling at 650 million miles per hour would be akin to one year on Earth.
Please don't expect me to check his math. I can barely total up my savings at Safeway. However, somehow one can imagine that technology will follow an inevitable path toward the unimaginable, a path that will change humanity even more profoundly than the laptop has changed love lives.
He does reportedly stress, however, that time travel will only be performed in a forward motion. Which, sadly, excludes a sudden reality show re-enactment of Mark Twain's "A Connecticut Yankee in King Arthur's Court."
Naturally, there is something stunningly attractive about the very idea of being able to skip generations by, well, flying through them. Imagine if some lucky humans had managed to avoid acid, platform boots, or the entire works of the Captain and Tennille. How might this have affected contemporary culture and the way it is promulgated onward by those who seem to know no better?
There is surely nothing remotely cranky or heretical about Hawking's prognostications. The only sadness is that so many of us will not be able to benefit from such exalted science.YoGa
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